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Welcome to the Gross Lab, where chemistry and biocatalysis come together to drive innovation! 

The central mantra of our group is sustainability through the implementation of green chemistry principles, such that our synthetic work is environmentally friendly.  We create sustainable materials by uniting green chemistry with biology, exploring biocatalysis, biobased polymer synthesis, biosurfactant design, microbial materials, fermentation, and enzyme engineering to build the next generation of sustainable technologies. Collaboration is at the heart of our lab, driving partnerships across disciplines and with industry to transform bold ideas into real-world impact.

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​Research foci include: 1) developing a better understanding of how enzyme promiscuity and selectivity for non-natural chemistries can be harnessed for polyester, peptide and bacterial cellulose synthesis, 2) tailoring biosurfactant structure for therapeutic use and commodity applications, 3) understand how microbially produced monomers and polymers can provide unique material properties, and 4) develop enzymes through protein engineering and immobilization for an array of functions, including the conversion of post-consumer plastics to value-added products.

Fall 2025 Featured News

​Sharing our science
Our team presented new advances in sustainable polymers at the ACS Fall 2025 National Meeting in Washington D.C., highlighting innovative approaches to green peptide synthesis and plastic recycling

Welcome, Sandhiya!
Sandhiya Thiagarajan joins the Gross group as a postdoctoral scholar, having completed her PhD in Chemical and Biological Engineering from the University of Alabama.


Getting out of the lab
 


Fellowship spotlight!
Congratulations to Amanda for being awarded the NIGMS T32 Training Grant for her proposed research in protease-catalyzed peptide synthesis

Recent 2025 Publications!

Congratulations to Kavita for her manuscript published in ChemSusChem titled: "Engineered Leaf-Branch Compost for Enhanced PET Depolymerization Over a Broad Temperature Range"

 

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Address: 
CBIS Lab - Center for Biotechnology and Interdisciplinary Studies, 1623 15th St, Troy, NY 12180
Cogswell Lab - Rensselaer Polytechnic Institute, 110 8th St., Troy, NY 12180-3590
 
Phone: 518-276-3734     
E-mailgrossr@rpi.edu

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